Normal fat, also known as subcutaneous fat, refers to the adipose tissue found beneath the skin throughout the body. It serves various essential functions, including insulation, energy storage, and cushioning of organs. Normal fat is distributed relatively evenly across the body and responds to diet and exercise in a typical manner. It can be reduced through caloric deficit and increased physical activity.

Lipedema fat, on the other hand, is a specific type of fat accumulation characterized by its abnormal distribution and resistance to traditional weight loss methods. Lipedema primarily affects the lower body, particularly the hips, buttocks, thighs, and sometimes the lower legs. Unlike normal fat, lipedema fat tends to accumulate disproportionately in these areas, resulting in a distinct pear-shaped or column-like appearance.